Influence of oophorectomy on glycemia and lipidogram

Autor: Renan Kleber Costa Teixeira, Daniel Haber Feijó, André Lopes Valente, Luan Teles Ferreira de Carvalho, Hícaro Donato Granhen, Andy Petroianu, Nara Macedo Botelho
Jazyk: angličtina
Rok vydání: 2018
Předmět:
Zdroj: Acta Cirúrgica Brasileira, Vol 33, Iss 5, Pp 415-419 (2018)
Druh dokumentu: article
ISSN: 0102-8650
DOI: 10.1590/s0102-865020180050000003
Popis: Abstract Purpose: To verify the influence of oophorectomy on lipidogram and glycemia. Methods: Fifty six female rats were divided into the following 7 groups (n = 8): group 1 - sham group, group 2 - oophorectomy 30 days, group 3 - oophorectomy 35 days, group 4 - oophorectomy 40 days, group 5 - oophorectomy 45 days, group 6 - oophorectomy 70 days, group 7 - oophorectomy 55 days. Animals were following by number of days according the group. Was evaluated the serum levels of glucose and lipid profile. Results: The oophorectomized rats presented higher glycemia. Groups 3, 4, 6 and 7 had a higher glycemia and LDL levels (except for group 6) and groups 6 and 7 had lowest levels of HDL. Group 7 had highest level of VLDL than oophorectomy groups. There was no difference in triglycerides levels. Conclusion: Oophorectomy was related to dyslipidemia and insulin resistance, mainly after 50th days.
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