Autor: |
Hisashi Akiyama, Caitlin M. Miller, Chelsea R. Ettinger, Anna C. Belkina, Jennifer E. Snyder-Cappione, Suryaram Gummuluru |
Jazyk: |
angličtina |
Rok vydání: |
2018 |
Předmět: |
|
Zdroj: |
Nature Communications, Vol 9, Iss 1, Pp 1-12 (2018) |
Druh dokumentu: |
article |
ISSN: |
2041-1723 |
DOI: |
10.1038/s41467-018-05899-7 |
Popis: |
Type I Interferon is thought to be a driving force for immune activation and T cell exhaustion during HIV infection. Here the authors show that intron-containing HIV RNA induces innate immune activation resulting in associated T cell dysfunction. |
Databáze: |
Directory of Open Access Journals |
Externí odkaz: |
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