Necrostatin-1: a promising compound for neurological disorders

Autor: Ke-qian Chen, Shu-zhi Wang, Hai-bo Lei, Xiang Liu
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Frontiers in Cellular Neuroscience, Vol 18 (2024)
Druh dokumentu: article
ISSN: 1662-5102
DOI: 10.3389/fncel.2024.1408364
Popis: Necrostatin-1, a small molecular alkaloid, was identified as an inhibitor of necroptosis in 2005. Investigating the fundamental mechanism of Necrostatin-1 and its role in various diseases is of great significance for scientific and clinical research. Accumulating evidence suggests that Necrostatin-1 plays a crucial role in numerous neurological disorders. This review aims to provide a comprehensive overview of the potential functions of Necrostatin-1 in various neurological disorders, offering valuable insights for future research.
Databáze: Directory of Open Access Journals