First-in-man feasibility study of a novel ingestible magnetically inflated balloon capsule for treatment of obesity
| Autor: | Hung Leng Kaan, Phuoc Thien Phan, Anthony Meng Huat Tiong, Muneaki Miyasaka, Soo Jay Phee, Khek Yu Ho |
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| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: | |
| Zdroj: | Endoscopy International Open, Vol 08, Iss 05, Pp E607-E610 (2020) |
| Druh dokumentu: | article |
| ISSN: | 2364-3722 2196-9736 |
| DOI: | 10.1055/a-1127-2991 |
| Popis: | Intragastric balloons (IGBs) are an established treatment option for obesity. Major barriers to dissemination of IGBs include lack of long-term efficacy outcomes, safety concerns, cost, and tolerability. We developed a novel ingestible magnetically inflated balloon capsule (IMI-BC) in hopes of overcoming these challenges. The IMI-BC is significantly cheaper than IGBs currently available on the market. We performed proof-of-concept animal studies and a first-in-human feasibility study to demonstrate the feasibility of inflating the IMI-BC using an external magnet. Further studies are currently being conducted to evaluate the safety, tolerability, and long-term efficacy of the IMI-BC. When fully developed, we anticipate that this device will benefit obese patients. |
| Databáze: | Directory of Open Access Journals |
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