IL-34 a Newly Discovered Cytokine
| Autor: | M.L. Castellani, A. Anogeianaki, P. Felaco, E. Toniato, M.A. De Lutiis, B. Shaik, M. Fulcheri, J. Vecchiet, S. Tetè, V. Salini, T.C. Theoharides, A. Caraffa, P. Antinolfi, S. Frydas, P. Conti, C. Cuccurullo, C. Ciampoli, G. Cerulli |
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| Jazyk: | angličtina |
| Rok vydání: | 2010 |
| Předmět: | |
| Zdroj: | European Journal of Inflammation, Vol 8 (2010) |
| Druh dokumentu: | article |
| ISSN: | 1721-727X 1721727X |
| DOI: | 10.1177/1721727X1000800202 |
| Popis: | In this study we describe some biological effects of IL-34, a newly discovered cytokine. We show that Il-34 stimulates monocyte cell viability and directly modulates the number and function of monocytes and regulates myeloid cell growth and differentiation. Moreover, since IL-34 in mice is involved in osteoporosis, an antagonist of this cytokine could be beneficial for the treatment of this disease. |
| Databáze: | Directory of Open Access Journals |
| Externí odkaz: |
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