Unusual manifestations of giant cell arteritis and granulomatosis with polyangiitis
| Autor: | Ryota Yoshimoto, Kitaru Tanaka, Tomoki Kawahata, Sayaka Takatori, Kyohei Takatori, Kohei Eguchi, Daisuke Fujishiro, Satoru Kodama, Atsushi Kobayashi, Kensaku Okamoto, Sayaka Yuzawa, Tsuguhito Ota, Yuichi Makino |
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| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: | |
| Zdroj: | Immunological Medicine, Vol 42, Iss 2, Pp 94-98 (2019) |
| Druh dokumentu: | article |
| ISSN: | 2578-5826 25785826 |
| DOI: | 10.1080/25785826.2019.1657377 |
| Popis: | Giant cell arteritis (GCA) is a type of large vessel vasculitis, and it involves the aorta, large vessels and terminal branches of the external carotid artery, especially the temporal artery. Temporal artery biopsy is a simple tool for the diagnosis of vasculitis, however, the histopathological findings do not always differentiate between the small-vessel vasculitis and GCA. We report the case of 72-year-old male who initially had a clinical diagnosis of GCA, then in the course of treatment, diagnostic histopathological approach revealed the necrotizing vasculitis with bronchocentric granulomatosis in the inflammatory nodule of the lung. The manifestations of patients with systemic vasculitis represent the disorders of multiple organ systems thus are diverse and may vary through the course of the disease. Presentation of unexpected features such as insufficient response to antibiotics, sinusitis, runny nose, discomfort of frontal region or pachymeningitis which anticipates re-evaluation of systemic vasculitis that may lead us to an appropriate diagnosis and the treatment. |
| Databáze: | Directory of Open Access Journals |
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