Pre-Stroke Modified Rankin Scale: Evaluation of Validity, Prognostic Accuracy, and Association with Treatment

Autor: Terence J. Quinn, Martin Taylor-Rowan, Aishah Coyte, Allan B. Clark, Stanley D. Musgrave, Anthony K. Metcalf, Diana J. Day, Max O. Bachmann, Elizabeth A. Warburton, John F. Potter, Phyo Kyaw Myint
Jazyk: angličtina
Rok vydání: 2017
Předmět:
Zdroj: Frontiers in Neurology, Vol 8 (2017)
Druh dokumentu: article
ISSN: 1664-2295
DOI: 10.3389/fneur.2017.00275
Popis: Background and purposeThe modified Rankin Scale (mRS) was designed to measure poststroke recovery but is often used to describe pre-stroke disability. We sought to evaluate three aspects of pre-stroke mRS: validity as a measure of pre-stroke disability; prognostic accuracy and association of pre-stroke mRS scores, and process of care.MethodsWe used data from a large, UK clinical registry. For analysis of validity, we compared pre-stroke mRS against other markers of pre-stroke function (age, comorbidity index, care needs). For analysis of prognostic accuracy, we described univariable and multivariable models comparing pre-stroke mRS and other prognostic variables against a variety of outcomes (early and late mortality, length of stay, institutionalization, incident complications). Finally, we described association of pre-stroke mRS and components of evidence-based stroke care (early neuroimaging, admission to stroke unit, assessment of swallow).ResultsWe analyzed data of 2,491 stroke patients. Concurrent validity analyses suggested statistically significant, but modest correlations between pre-stroke mRS and chosen variables (rho >0.40; p
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