Unraveling Complexity: Delving into a Novel Pigmented Epithelioid Melanocytoma Case

Autor: Vijaya V. Mysorekar, Nidha Gaffoor, B N Divyashree, S Sharath Chandra Tejas
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Indian Dermatology Online Journal, Vol 15, Iss 6, Pp 996-999 (2024)
Druh dokumentu: article
ISSN: 2229-5178
2249-5673
DOI: 10.4103/idoj.idoj_726_23
Popis: Pigmented epithelioid melanocytoma (PEM) is a rare and diagnostically challenging skin neoplasm. Differentiating this lesion from melanoma is challenging due to overlapping clinical, histopathological, and immunohistochemical features. Some PEMs have a benign course, while others may be associated with more aggressive behaviour and have potential for local recurrence or distant metastasis. So, careful evaluation and follow-up are crucial for individuals with a diagnosis of PEM. This case study focuses on a 42-year-old woman with a gradually enlarging, dark, pigmented gluteal lesion. Histopathological analysis following complete excision showed nodular proliferation of spindled and epithelioid melanocytes in the dermis, extending into subcutaneous fat. Cellular atypia or mitotic figures were absent, confirming the diagnosis as PEM. This case underscores the intricate balance between monitoring and intervention in complex dermatological cases, shedding light on diagnostic challenges and ultimately striving for improved patient care.
Databáze: Directory of Open Access Journals
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