INTERRELATION AND INTERDEPENDENCE OF CLINICAL SYNDROMES FROM DEGREE OF STENOSIS OF VERTEBRAL CANAL ON LUMBAR LEVEL

Autor: Z. V. Koshkariova, V. A. Sorokovikov, A. V. Gorbunov, V. G. Brukhanov, L. V. Rodionova, O. V. Skliarenko
Jazyk: ruština
Rok vydání: 2013
Předmět:
Zdroj: Acta Biomedica Scientifica, Vol 0, Iss 2(2), Pp 29-33 (2013)
Druh dokumentu: article
ISSN: 2541-9420
2587-9596
Popis: There were 81 patients with vertebral canal stenosis under observation. All patients underwent complex examination: study of clinical neurological status; review spondylography of lumbar part of the spine; MRI of lumbar part of the spine; multispiral CT with myelography of lumbar part of the spine; functional spondylography of lumbar part of the spine with load; the study of morphometry of vertebral canal, dural sack and vertebra body by designed method; the study of acute phase proteins in blood. Conducted complex research revealed that improved classification of stenosis of vertebral canal reflects direct dependence of severity of clinical-neurological manifestations from the degree of stenosis. It also has been marked that reduced concentration of α2-macroglobulin in blood manifests itself in negative regulation of cells of immune system. And an increase of classic rheumatoid factor (Ig M-RF), α1-antitripsin and α1-acid glycoprotein in blood serum leads to reduction of inflammatory and immune response. Revealed direct co-dependence of severity of disease and degree of stenosis gives a possibility to develop more precise program of conservative and surgical treatment.
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