Does body mass index impact assisted reproductive technology treatment outcomes in gestational carriers

Autor: Noga Fuchs Weizman, Miranda K. Defer, Janice Montbriand, Julia M. Pasquale, Adina Silver, Clifford L. Librach
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: Reproductive Biology and Endocrinology, Vol 18, Iss 1, Pp 1-9 (2020)
Druh dokumentu: article
ISSN: 1477-7827
DOI: 10.1186/s12958-020-00602-2
Popis: Abstract Background The purpose of this study was to assess whether increased body mass index (BMI) negatively affects assisted reproductive technology (ART) outcomes among gestational carriers. Methods A retrospective matched case-control cohort, including all gestational carrier (GC) cycles performed at CReATe Fertility Centre (Toronto, ON, Canada) between 2003 and 2016. Setting A Canadian fertility clinic, with a large surrogacy program. Patients All gestational carriers that had undergone a cycle completed to a transfer at our clinic, and had BMI and outcome data available, were matched by BMI to infertile patients treated at our clinic during the same years provided they had undergone a cycle completed to a transfer, and had outcomes data available. Interventions None. Main outcome measures Clinical pregnancies rates, miscarriage rates and live birth rates. Results BMI was not a reliable prediction factor of any of the measured outcomes. Importantly, the gestational carrier population had better outcomes and a significantly lower overall incidence of maternal, fetal and neonatal complications when compared with infertile patients, treated at our clinic during the same years. Conclusion BMI is not a reliable predictor of outcomes among gestational carriers.
Databáze: Directory of Open Access Journals
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