Serological evaluation of immune effect of inactivated COVID-19 vaccine in adult population in Deqing County, Huzhou City, Zhejiang Province

Autor: MAO Chuanwu, CHEN Yingfeng, ZHANG Li, XIE Yuyang, DONG Xiaolian, JIANG Lufang, JIANG Qingwu
Jazyk: čínština
Rok vydání: 2022
Předmět:
Zdroj: Shanghai yufang yixue, Vol 34, Iss 11, Pp 1118-1122 (2022)
Druh dokumentu: article
ISSN: 1004-9231
DOI: 10.19428/j.cnki.sjpm.2022.22105
Popis: ObjectiveTo investigate the specific anti-SARS-CoV-2 antibody in adults and above after initial vaccination with inactivated COVID-19 vaccine, and determine the influencing factors.MethodsIn this study, residents aged 18 and above who had completed two doses of inactivated COVID-19 vaccine in Deqing County, Huzhou City, Zhejiang Province were included. Information such as gender, age, type of vaccine and vaccination time were collected, and serum specimens were sampled. Anti-SARS-CoV-2 receptor binding domain (RBD) antibody was quantitatively examined by enzyma-linked immunosorbent assay (ELISA) and influencing factors were determined.ResultsThe median concentration of anti-SARS-CoV-2 IgG antibody in the residents vaccinated with an inactivated booster vaccine was higher than that in those vaccinated with only two doses of COVID-19 vaccine or single dose (P
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