Fatigue is highly prevalent in patients with COPD and correlates poorly with the degree of airflow limitation

Autor: Yvonne M. J. Goërtz, Martijn A. Spruit, Alex J. Van ‘t Hul, Jeannette B. Peters, Maarten Van Herck, Nienke Nakken, Remco S. Djamin, Chris Burtin, Melissa S. Y. Thong, Arnold Coors, Yvonne Meertens-Kerris, Emiel F. M. Wouters, Judith B. Prins, Frits M. E. Franssen, Jean W. M. Muris, Lowie E. G. W. Vanfleteren, Mirjam A. G. Sprangers, Daisy J. A. Janssen, Jan H. Vercoulen
Jazyk: angličtina
Rok vydání: 2019
Předmět:
Zdroj: Therapeutic Advances in Respiratory Disease, Vol 13 (2019)
Druh dokumentu: article
ISSN: 1753-4666
17534666
DOI: 10.1177/1753466619878128
Popis: Background: The objective of this study was to compare fatigue levels between subjects with and without COPD, and to investigate the relationship between fatigue, demographics, clinical features and disease severity. Methods: A total of 1290 patients with COPD [age 65 ± 9 years, 61% male, forced expiratory volume in 1 s (FEV1) 56 ± 19% predicted] and 199 subjects without COPD (age 63 ± 9 years, 51% male, FEV1 112 ± 21% predicted) were assessed for fatigue (Checklist Individual Strength-Fatigue), demographics, clinical features and disease severity. Results: Patients with COPD had a higher mean fatigue score, and a higher proportion of severe fatigue (CIS-Fatigue score 35 ± 12 versus 21 ± 11 points, p
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