Lymph Node Biopsy Specimens and Diagnosis of Cat-scratch Disease
| Autor: | Jean-Marc Rolain, Hubert Lepidi, Michel Zanaret, Jean-Michel Triglia, Gérard Michel, Pascal-Alexandre Thomas, Michèle Texereau, Andreas Stein, Anette Romaru, François Eb, Didier Raoult |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2006 |
| Předmět: | |
| Zdroj: | Emerging Infectious Diseases, Vol 12, Iss 9, Pp 1338-1344 (2006) |
| Druh dokumentu: | article |
| ISSN: | 1080-6040 1080-6059 |
| DOI: | 10.3201/eid1209.060122 |
| Popis: | We report microbiologic analysis of 786 lymph node biopsy specimens from patients with suspected cat-scratch disease (CSD). The specimens were examined by standard, cell culture, and molecular methods. Infectious agents were found in samples from 391 (49.7%) of 786 patients. The most commonly identified infectious agent was Bartonella henselae (245 patients, 31.2%), the agent of CSD. Mycobacteriosis was diagnosed in 54 patients (6.9%) by culture and retrospectively confirmed by using a specific real-time PCR assay. Neoplasm was diagnosed in 181 specimens suitable for histologic analysis (26.0%) from 47 patients. Moreover, 13 patients with confirmed Bartonella infections had concurrent mycobacteriosis (10 cases) or neoplasm (3 cases). A diagnosis of CSD does not eliminate a diagnosis of mycobacteriosis or neoplasm. Histologic analysis of lymph node biopsy specimens should be routinely performed because some patients might have a concurrent malignant disease or mycobacteriosis. |
| Databáze: | Directory of Open Access Journals |
| Externí odkaz: |
|