| Autor: |
Sumiyo Okawa, Kenichi Komada, Yasunori Ichimura, Masaya Sugiyama, Hung Thai Do, Huy Xuan Le, Thanh Tien Hoang, Trieu Bao Nguyen, Mai Kim Huynh, Hang Thi Hai Hoang, Nhu Anh Thi Tran, Thieu Hoang Le, Quyet Thi Ngo, Shinsuke Miyano, Yuta Yokobori, Yosuke Inoue, Tetsuya Mizoue, Masahiko Hachiya |
| Jazyk: |
angličtina |
| Rok vydání: |
2022 |
| Předmět: |
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| Zdroj: |
International Journal of Infectious Diseases, Vol 125, Iss , Pp 51-57 (2022) |
| Druh dokumentu: |
article |
| ISSN: |
1201-9712 |
| DOI: |
10.1016/j.ijid.2022.10.011 |
| Popis: |
Objectives: This study aimed to determine the agreement between a rapid diagnostic test (RDT) and a dried blood spot (DBS)-based electrochemiluminescence immunoassay (ECLIA) of hepatitis B surface antigen and to compare the costs of conducting serosurveys using RDTs and DBS in a field setting. Methods: A serosurvey was conducted in the South Central Coast region of Vietnam in May 2019. Participants aged 1-39 years were recruited using a four-stage random sampling method and tested for hepatitis B surface antigen using an RDT kit (Alere Determine) and a DBS-based ECLIA. The agreement between the RDT and the DBS-based ECLIA was assessed using cross-tabulation and Cohen kappa. Cost data were categorized by input (personnel, transportation, field consumables, laboratory consumables, and capital item/overhead) and survey phase (survey preparation, data/biospecimen collection, laboratory testing, and coordination). Results: A total of 2072 participants were analyzed. There was a 99% agreement between the RDT and the DBS-based ECLIA results, with a Cohen kappa of 0.9. The estimated cost of conducting a serosurvey by DBS was UD $75,291, whereas RDT was $53,182. Conclusion: RDTs and DBS-based ECLIA provide test results with high agreements. RDTs are a better option in terms of cost, whereas the DBS-based ECLIA may be useful when evaluating multiple infectious diseases. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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