Pneumonia rebound after stopping steroid in a patient with COVID‐19: A case report

Autor: Po‐Hao Chen, Chun‐Yuan Cheng, Li‐Fu Li, Chung‐Chieh Yu
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Respirology Case Reports, Vol 9, Iss 11, Pp n/a-n/a (2021)
Druh dokumentu: article
ISSN: 2051-3380
DOI: 10.1002/rcr2.869
Popis: Abstract Patients with severe coronavirus disease 2019 (COVID‐19) can develop a systemic inflammatory response that can lead to lung injury and multisystem organ dysfunction. The current treatment guideline recommends the use of corticosteroids in patients who require supplemental oxygen or are mechanically ventilated. This study reports a patient with severe COVID‐19 pneumonia. Initially, the patient was treated with dexamethasone for 10 days and remdesivir for 5 days. There was clinical improvement following the treatments. However, on day 15, the patient experienced rebound pneumonia and clinical deterioration. His clinical condition improved until dexamethasone was re‐administered. This case demonstrates the rebound phenomenon after the steroid was discontinued. The duration and timing of steroids are crucial to reduce the risk of prolonged systemic inflammation and rebound pneumonia.
Databáze: Directory of Open Access Journals