Different damage patterns of retinal nerve fiber layer and ganglion cell-inner plexiform layer between early glaucoma and non-glaucomatous optic neuropathy
| Autor: | Hui Xiao, Xing Liu, Ping Lian, Ling-Ling Liao, Yi-Min Zhong |
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| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: | |
| Zdroj: | International Journal of Ophthalmology, Vol 13, Iss 6, Pp 893-901 (2020) |
| Druh dokumentu: | article |
| ISSN: | 2222-3959 2227-4898 |
| DOI: | 10.18240/ijo.2020.06.06 |
| Popis: | AIM: To compare the damage pattern of the peripapillary retinal nerve fiber layer (pRNFL) and the macular ganglion cell-inner plexiform layer (mGCIPL) between early glaucomatous and non-glaucomatous optic neuropathy (EGON and NGON). METHODS: It is a cross-sectional study. Thirty-eight healthy controls, 74 EGONs and 70 NGONs with comparable average pRNFL loss were included. The NGON group included 23 eyes of optic neuritis (ON), 13 eyes of hereditary optic neuropathy (HON), 19 eyes of toxic optic neuropathy (TON) and 15 eyes of compressive neuropathy (CON). The sectoral pRNFL and mGCIPL thickness obtained by high definition optical coherence tomography were analyzed. RESULTS: Compared to normal controls, the pRNFL thickness in all quadrants showed a decrease in both EGON and NGON group (P0.05). The mGCIPL of EGON and NGON group were thinner than control group (P |
| Databáze: | Directory of Open Access Journals |
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