Incidence of community-acquired pneumonia hospitalisation in persons with bronchiectasis during the COVID-19 lockdown in Denmark: a retrospective cohort study

Autor: Pradeesh Sivapalan, Josefin Eklöf, Jens-Ulrik Stæhr Jensen, Mohamad Isam Saeed, Alexander Svorre Jordan, Valdemar Rømer, Martina Bjørka Fosgaard, Louise Lindhardt Toennesen, Tina Gissel, Sofie Lock Johansson
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: BMJ Open Respiratory Research, Vol 10, Iss 1 (2023)
Druh dokumentu: article
ISSN: 2052-4439
DOI: 10.1136/bmjresp-2022-001517
Popis: Background Persons with bronchiectasis have a high risk of community-acquired pneumonia. Social distancing measures, implemented to prevent the spreading of SARS-CoV-2, could potentially reduce the incidence of other infectious diseases.Research question Was the COVID-19 lockdown period, along with accompanying social distancing measures, associated with reduced hospital admissions for community-acquired pneumonia and decreased overall mortality rates among individuals with bronchiectasis?Methods Social distancing measures were introduced in Denmark by 12 March 2020 and were preserved until 20 May 2020 (social distancing period), after which the measures were gradually dismissed. The study included all adults (≥18 years) with bronchiectasis residing in Denmark. Confirmed cases of SARS-CoV-2 infection were excluded. We retrospectively investigated the incidence of community-acquired pneumonia hospital admission, death of all causes and respiratory antibiotic treatment in the 10-week social distancing period in 2020, compared with the same dates in 2019. 9344 persons were included in the study.Results In the social distancing period, the incidence rate of pneumonia-hospitalisation per 10 000 person-weeks was 9.2 compared with 13.8 in the reference period. This reduction corresponds to an incidence rate ratio (IRR) of 0.67 (95% CI 0.51 to 0.88, p
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