| Autor: |
Sopan Nangare, Sayali Patil, Kalyani Chaudhari, Zamir Khan, Ashwini Patil, Pravin Patil |
| Jazyk: |
angličtina |
| Rok vydání: |
2023 |
| Předmět: |
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| Zdroj: |
Nano Biomedicine and Engineering, Vol 15, Iss 1, Pp 1-13 (2023) |
| Druh dokumentu: |
article |
| ISSN: |
2150-5578 |
| DOI: |
10.26599/NBE.2023.9290005 |
| Popis: |
Quercetin can help with a variety of health problems. Most methods for measuring quercetin in biological fluids are characterized by low sensitivity and selectivity. The employment of metal–organic frameworks in sensor applications with carbon-based materials ushers in a new era. In this study, blue fluorescent graphene quantum dots (GQDs) embedded in a UiO-66-NH2 metal–organic framework-based nanoprobe (GQDs@UiO-66-NH2) were constructed for quercetin sensing. Initially, maize husk was used to produce blue fluorescent GQDs, whereas zirconium tetrachloride and 2-aminoterephthalic acid were used to synthesize extremely luminous UiO-66-NH2. The addition of quercetin to GQDs@UiO-66-NH2 leads to fluorescence dampening due to the adsorption potential of UiO-66-NH2. The complexation of zirconium ions with the 3-OH and 4-C＝O functionalities of quercetin resulted in fluorescence quenching. The sensor has a linear concentration range and limit of detection for quercetin of 50–500 and 2.82 ng/mL, respectively. The nanoprobe’s usefulness for quercetin detection was then validated by a selectivity investigation in the presence of interfering chemicals. Furthermore, the percentage relative standard deviations were 4.20% and 2.90%, respectively, indicating great stability and repeatability. Fluorescence “Turn-On–Off” nanoprobes provide a simple, quick, sensitive, and selective method for monitoring quercetin. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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