| Autor: |
O. Abeyakoon, R. Woitek, M.G. Wallis, P.L. Moyle, S. Morscher, N. Dahlhaus, S.J. Ford, N.C. Burton, R. Manavaki, I.A. Mendichovszky, J. Joseph, I. Quiros-Gonzalez, S.E. Bohndiek, F.J. Gilbert |
| Jazyk: |
angličtina |
| Rok vydání: |
2022 |
| Předmět: |
|
| Zdroj: |
Photoacoustics, Vol 27, Iss , Pp 100383- (2022) |
| Druh dokumentu: |
article |
| ISSN: |
2213-5979 |
| DOI: |
10.1016/j.pacs.2022.100383 |
| Popis: |
Combining optoacoustic (OA) imaging with ultrasound (US) enables visualisation of functional blood vasculature in breast lesions by OA to be overlaid with the morphological information of US. Here, we develop a simple OA feature set to differentiate benign and malignant breast lesions. 94 female patients with benign, indeterminate or suspicious lesions were recruited and underwent OA-US. An OA-US imaging feature set was developed using images from the first 38 patients, which contained 14 malignant and 8 benign solid lesions. Two independent radiologists blindly scored the OA-US images of a further 56 patients, which included 31 malignant and 13 benign solid lesions, with a sensitivity of 96.8% and specificity of 84.6%. Our findings indicate that OA-US can reveal vascular patterns of breast lesions that indicate malignancy using a simple feature set based on single wavelength OA data, which is therefore amenable to application in low resource settings for breast cancer management. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
|
