High-density lipoprotein cholesterol concentration and acute kidney injury after noncardiac surgery

Autor: Yan Zhou, Hong-Yun Yang, Hui-Li Zhang, Xiao-Jin Zhu
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: BMC Nephrology, Vol 21, Iss 1, Pp 1-7 (2020)
Druh dokumentu: article
ISSN: 1471-2369
DOI: 10.1186/s12882-020-01808-7
Popis: Abstract Background Abnormal High-density Lipoprotein Cholesterol Concentration is closely related to postoperative acute kidney injury (AKI) after cardiac surgeries. The purpose of this study was to analyze the relationship between High-density Lipoprotein Cholesterol Concentration and acute kidney injury after non-cardiac surgeries. Method This was a single-center cohort study for elective non-cardiac non-kidney surgery from January 1, 2012, to December 31, 2017. The endpoint was the occurrence of acute kidney injury (AKI) 7 days postoperatively in the hospital. Preoperative serum High-density Lipoprotein Cholesterol Concentration was examined by multivariate logistic regression models before and after propensity score weighting analysis. Results Of the 74,284 surgeries, 4.4% (3159 cases) suffered acute kidney injury. The odds ratio for HDL (0.96–1.14 as reference, 1.35) was 1.28 (1.14–1.41), P 1.03 as reference) was associated with increased risk of postoperative AKI, with odds ratio 1.40 (1.27 ~ 1.52), P
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