Calcifications in Thyroid Ultrasonography and Thyroid Carcinoma
| Autor: | Maria Christina D. Sio, Jacqueline Austine U. Uy, Ronaldo G. Soriano |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2014 |
| Předmět: | |
| Zdroj: | Philippine Journal of Otolaryngology Head and Neck Surgery, Vol 29, Iss 2 (2014) |
| Druh dokumentu: | article |
| ISSN: | 1908-4889 2094-1501 |
| DOI: | 10.32412/pjohns.v29i2.413 |
| Popis: | Background: Thyroid nodules are a common disease entity occurring in 5-10% of the general population and increasing with age. Their detection on ultrasonography ranges from 13% to 67%. Calcifications on ultrasound may occur in both benign and malignant diseases, but have been cited for increased risk of thyroid carcinoma. Objective: To determine the association of calcifications found on thyroid ultrasonography and the different types of calcifications with thyroid carcinoma. Method: Study Design: Retrospective Study Setting: Tertiary Private Hospital Participants: 126 patients with pre-operative thyroid or neck ultrasonography who subsequently underwent thyroidectomy (total or subtotal, with or without frozen section) were selected from a database covering a one-year period from January to December 2012. The presence and type of calcification on ultrasonography was correlated with the final histopathologic report for a diagnosis of thyroid carcinoma. Sensitivity, specificity, positive and negative predictive values were obtained. Results: 51 out of 126 studies (40%) were observed to have calcifications of any description, in both histologically benign (41%) and malignant (59%) nodules. Calcifications seen in malignancy arose from papillary carcinoma (86%). Follicular carcinoma and others (Plasmacytoma and Lymphoma) accounted for 7% each. The peripheral type of calcification was most prevalent accounting for 37% (11 out of 30). The sensitivity of detecting calcifications on ultrasonography is 58.82%, specificity 81.33%, positive predictive value 68.18% and negative predictive value 74.38%. Chi square test computed was 21.54 (P |
| Databáze: | Directory of Open Access Journals |
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