Energy Regulation in Inflammatory Sarcopenia by the Purinergic System

Autor:	Miguel Marco-Bonilla, Maria Fresnadillo, Raquel Largo, Gabriel Herrero-Beaumont, Aránzazu Mediero
Jazyk:	angličtina
Rok vydání:	2023
Předmět:	adenosine muscle sarcopenia Biology (General) QH301-705.5 Chemistry QD1-999
Zdroj:	International Journal of Molecular Sciences, Vol 24, Iss 23, p 16904 (2023)
Druh dokumentu:	article
ISSN:	1422-0067 1661-6596
DOI:	10.3390/ijms242316904
Popis:	The purinergic system has a dual role: the maintenance of energy balance and signaling within cells. Adenosine and adenosine triphosphate (ATP) are essential for maintaining these functions. Sarcopenia is characterized by alterations in the control of energy and signaling in favor of catabolic pathways. This review details the association between the purinergic system and muscle and adipose tissue homeostasis, discussing recent findings in the involvement of purinergic receptors in muscle wasting and advances in the use of the purinergic system as a novel therapeutic target in the management of sarcopenia.
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/fcaaf566506d4f6c93b90a36a5b899d1 Zobrazit plný text záznamu View record in DOAJ Plný text ve formátu PDF Plný text ve formátu HTML
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