| Autor: |
Reuter Thomas, Ponomarev Igor |
| Jazyk: |
angličtina |
| Rok vydání: |
2021 |
| Předmět: |
|
| Zdroj: |
Current Directions in Biomedical Engineering, Vol 7, Iss 2, Pp 355-358 (2021) |
| Druh dokumentu: |
article |
| ISSN: |
2364-5504 |
| DOI: |
10.1515/cdbme-2021-2090 |
| Popis: |
Cartilage constructs produced by SFCTtechnology provide promising opportunities to restore cartilage defects. Mechanical parameters of soft tissues are explicit markers for quantitative tissue characterization. In this study, we present a biphasic 3D-FE-based method to determine the biomechanical properties of SFCT from stress relaxation compression tests (ε = 20 %, t = 3400 s) whereby cartilaginous tissue is modeled as a biphasic material with tension-compression nonlinearity (BMTCN). The FE-model computation was optimized by exploiting the axial symmetry and mesh resolution. The R² of the fit results varies between 0.970 and 0.983. The Young’s and fiber modulus determined from SFCT are 37-times and 5-times lower than from native articular cartilage, respectively. Permeability, on the other hand, is 11-times higher than from native articular cartilage. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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