Late Diagnosis of Disseminated Sporothrix brasiliensis Infection with Bone Marrow Involvement in an HIV-Negative Patient

Autor: Vanessa Caroline Randi Magalhães, Salene Angelini Colombo, Gustavo José Cota Freitas, Alexandre Sampaio Moura, Flávia Cardoso Lopez Vieira, Ana Cláudia Lyon, Maria Isabel Azevedo, Nalu Teixeira de Aguiar Peres, Daniel Assis Santos
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Pathogens, Vol 11, Iss 12, p 1516 (2022)
Druh dokumentu: article
ISSN: 2076-0817
DOI: 10.3390/pathogens11121516
Popis: Sporotrichosis is a fungal disease that causes symptoms similar to those of other infectious and non-infectious diseases, making diagnosis difficult and challenging. Here, we report a case of an HIV-negative patient presenting disseminated sporotrichosis with widespread cutaneous lesions mimicking pyoderma gangrenosum, with bone marrow infection, pancytopenia, and hemophagocytic syndrome. However, all the clinical manifestations and a bacterial coinfection delayed the request for a fungal diagnosis. Therefore, sporotrichosis should always be investigated in patients from endemic areas presenting with widespread cutaneous lesions associated with pancytopenia.
Databáze: Directory of Open Access Journals