Functional roles of circular RNAs in lung injury

Autor: Fei-Fei Gao, Dian-Qing Chen, Yue-Tong Jiang, Cui-Fei Han, Bi-Yun Lin, Zhan Yang, Juan-Hua Quan, Ying-Huan Xiong, Xin-Tian Chen
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Frontiers in Pharmacology, Vol 15 (2024)
Druh dokumentu: article
ISSN: 1663-9812
DOI: 10.3389/fphar.2024.1354806
Popis: Lung injury leads to respiratory dysfunction, low quality of life, and even life-threatening conditions. Circular RNAs (circRNAs) are endogenous RNAs produced by selective RNA splicing. Studies have reported their involvement in the progression of lung injury. Understanding the roles of circRNAs in lung injury may aid in elucidating the underlying mechanisms and provide new therapeutic targets. Thus, in this review, we aimed to summarize and discuss the characteristics and biological functions of circRNAs, and their roles in lung injury from existing research, to provide a theoretical basis for the use of circRNAs as a diagnostic and therapeutic target for lung injury.
Databáze: Directory of Open Access Journals