Peripapillary RNFL cross-sectional area and its association with other parameters in a Chinese population

Autor: Yan Yanni, Wang Qian, Wei Wenbin
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: BMC Ophthalmology, Vol 24, Iss 1, Pp 1-6 (2024)
Druh dokumentu: article
ISSN: 1471-2415
DOI: 10.1186/s12886-024-03481-y
Popis: Abstract Background Quantitative analysis of retinal nerve fibers is important for the diagnosis and treatment of optic nerve diseases. Peripapillary retinal nerve fiber layer (RNFL) cross-sectional area may give a more accurate quantitative assessment of retinal nerve fibers than RNFL thickness but there have been no previous reports of the peripapillary RNFL cross-sectional area or other parameters. The purpose of the current study was to determine peripapillary RNFL cross-sectional area and its association with other factors in an adult Chinese population. Methods RNFL cross-sectional area was measured during peripapillary circular optical coherence tomography (OCT) scan with a diameter of 12° centered on the optic disc. Correlation between RNFL cross-sectional area and other parameters was evaluated by linear regression analysis in a cross-sectional study of an adult Chinese population. Results A total of 2404 eyes from 2404 subjects were examined. Multivariate linear regression analysis showed that larger RNFL cross-sectional area correlated with younger age (p
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