Prevalence of metabolic dysfunction–associated fatty liver disease among patients with diabetic kidney disease: a systematic review and meta-analysis

Autor: Mohammad Rahmanian, Niloofar Deravi, Mohadeseh Poudineh, Amirhossein Poopak, Seyed Nooshan Mirmohammadali, Saba Fekrvand, Kiana Tadbir, Sara Ebrahimian, Nikan Zargarzadeh, Marzieh Pirzadeh, Amir Abdi, Fatemeh Dehghani Firouzabadi, Jeffrey I. Mechanick
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Egyptian Liver Journal, Vol 14, Iss 1, Pp 1-9 (2024)
Druh dokumentu: article
ISSN: 2090-6226
DOI: 10.1186/s43066-024-00393-w
Popis: Abstract Background Mechanistic relationships between metabolic dysfunction–associated fatty liver disease (MAFLD) and chronic kidney disease are well characterized. Specifically, in type 2 diabetes (T2D), insulin resistance leads to MAFLD, and hyperglycemia leads to microvascular complications such as diabetic kidney disease (DKD). This systematic review and meta-analysis aims to describe the specific association between MAFLD and DKD for the first time. Methods PubMed, Web of Science, Google Scholar, and Scopus databases were searched up to February 2023 to identify relevant published articles. After screening the titles, abstracts, and full texts of the retrieved articles, cross-sectional studies and cohorts reporting on MAFLD in patients with DKD were identified and then analyzed. Results A total of 2615 articles were identified, of which 5 had sufficient data and fulfilled the eligibility criteria for meta-analysis. A total of 2345 patients with DKD were in the included studies. The prevalence rates of radiologically diagnosed MAFLD among patients with DKD ranged from 25 to 96%. The pooled prevalence rate of radiologically diagnosed MAFLD among patients with DKD was 0.55 (95% CI = 0.21–0.89, I 2 = 99.79%, P-value
Databáze: Directory of Open Access Journals
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