Histopathological parameters in pterygia and significant clinical correlations

Autor: Ahmed Mohamed Reda, Yasmine Maher Mohamed Shaaban, Somaia Ahmad Saad El-Din
Jazyk: angličtina
Rok vydání: 2018
Předmět:
Zdroj: Journal of Ophthalmic & Vision Research, Vol 13, Iss 2, Pp 110-118 (2018)
Druh dokumentu: article
ISSN: 2008-322X
DOI: 10.4103/jovr.jovr_31_17
Popis: Purpose: To evaluate the clinical and histopathological parameters of pterygium to determine significant correlations between parameters that can affect management strategies. Methods: A total of 47 pterygia were clinically examined and excised for histopathological evaluation of epithelial and stromal changes. Some samples were immunostained with P53 (a protein of 53 kilodalton used as dysplastic epithelial marker), CD20 (CD/cluster of differentiation, are group of surface receptors providing targets for cellular immunophenotyping, CD20 as a B lymphocyte marker), CD 3 (as T lymphocyte marker) or vascular endothelial growth factor (VEGF/as vascular marker). Results: Most patients were male (59.6%). Cosmetic complaints (83%), grade II redness (61.7%), grade 2 extension (63.8), and associated astigmatism of
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