Sporadic Shiga Toxin–Producing Escherichia coli–Associated Pediatric Hemolytic Uremic Syndrome, France, 2012–2021

Autor: Gabrielle Jones, Patricia Mariani-Kurkdjian, Aurélie Cointe, Stéphane Bonacorsi, Sophie Lefèvre, François-Xavier Weill, Yann Le Strat
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Emerging Infectious Diseases, Vol 29, Iss 10, Pp 2054-2064 (2023)
Druh dokumentu: article
ISSN: 1080-6040
1080-6059
DOI: 10.3201/eid2910.230382
Popis: Shiga toxin–producing Escherichia coli–associated pediatric hemolytic uremic syndrome (STEC-HUS) remains an important public health risk in France. Cases are primarily sporadic, and geographic heterogeneity has been observed in crude incidence rates. We conducted a retrospective study of 1,255 sporadic pediatric STEC-HUS cases reported during 2012–2021 to describe spatiotemporal dynamics and geographic patterns of higher STEC-HUS risk. Annual case notifications ranged from 109 to 163. Most cases (n = 780 [62%]) were in children 5 annual space-time clusters. The results of this study have numerous implications for outbreak detection and investigation and research perspectives to improve knowledge of environmental risk factors associated with geographic disparities in STEC-HUS in France.
Databáze: Directory of Open Access Journals