| Autor: |
Alejandra Pérez-Montes de Oca, María Teresa Julián, Guillem Pera, Llorenç Caballería, Rosa Morillas, Pere Torán, Carmen Expósito, Josep Franch-Nadal, Didac Mauricio, Nuria Alonso |
| Jazyk: |
angličtina |
| Rok vydání: |
2022 |
| Předmět: |
|
| Zdroj: |
Frontiers in Endocrinology, Vol 13 (2022) |
| Druh dokumentu: |
article |
| ISSN: |
1664-2392 |
| DOI: |
10.3389/fendo.2022.971864 |
| Popis: |
IntroductionSexual dimorphism has been reported in non-alcoholic fatty liver disease (NAFLD), similar to the sex differences evident with cardiovascular disease. Type 2 diabetes mellitus (T2D) significantly increases the risk and severity of NAFLD, but there is scarce information on whether T2D or altered glucose metabolism can modify the prevalence of NAFLD in men and women of reproductive age.PurposeTo investigate the relationship between age, sex and NAFLD in subjects with and without dysglycemia.Materials and methodsWe analyzed 2,790 patients. NAFLD was characterized using established diagnostic criteria: one or more positive results on the fatty liver index and hepatic ultrasound. Liver fibrosis (liver stiffness measurement [LSM] ≥8.0 kPa) was assessed by Fibroscan®. For analysis purposes, we included both T2D and prediabetes under the predefined condition of dysglycemia.ResultsThe global prevalence of NAFLD was higher in men than in women (50% and 34%; P |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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