Association between serum vitamin D status and severity of liver cirrhosis: implications for therapeutic targeting in Nigerian patients

Autor:	Winnifred Njideka Adiri, Bruno Basil, Chinwe Philomena Onyia, Promise Asogwa, Oluchi Joy Ugwuanyi, Olive Obienu, Uchenna Nkemdilim Ijoma, Slyvester Chuks Nwokediuko
Jazyk:	angličtina
Rok vydání:	2024
Předmět:	Liver cirrhosis Nigerian Severity Therapeutic targeting Vitamin D Diseases of the digestive system. Gastroenterology RC799-869
Zdroj:	BMC Gastroenterology, Vol 24, Iss 1, Pp 1-10 (2024)
Druh dokumentu:	article
ISSN:	1471-230X
DOI:	10.1186/s12876-024-03353-1
Popis:	Abstract Background Liver cirrhosis is a chronic and progressive liver disease with significant global health implications. Recent evidence suggests an association between serum vitamin D levels and the severity of liver cirrhosis, potentially serving as a therapeutic target. This study aimed to investigate the relationship between serum vitamin D status and the severity of liver cirrhosis in a population of Nigerian patients. Methods This analytical, cross-sectional study involved 201 participants, including 103 with liver cirrhosis and 98 age- and sex-matched controls. Serum vitamin D was measured using ELISA, with deficiency defined as
Databáze:	Directory of Open Access Journals
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