Poly[3-(3,4-dihydroxyphenyl)glyceric Acid], A New Biologically Active Polymer from Symphytum Asperum Lepech. and S.Caucasicum Bieb. (Boraginaceae)

Autor: A. Usov, A. Shashkov, K. Mulkijanyan, I. Targamadze, E. Kemertelidze, V. Barbakadze
Jazyk: angličtina
Rok vydání: 2005
Předmět:
Zdroj: Molecules, Vol 10, Iss 9, Pp 1135-1144 (2005)
Druh dokumentu: article
ISSN: 1420-3049
DOI: 10.3390/10091135
Popis: Two high-molecular water-soluble preparations with high anticomplementary, antioxidant, antilipoperoxidant and antiinflammatory activities were isolated from the roots of Symphytum asperum and S. caucasicum. Their main chemical constituent was found to be poly[oxy-1-carboxy-2-(3,4-dihydroxyphenyl)ethylene], according to IR and NMR spectroscopy. The Symphytum high-molecular preparations can modulate in vitro B- chronic lymphocytic leukaemia (B-CLL) cells apoptosis and cell cycle progression.
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