DNA methylation and hydroxymethylation characterize the identity of D1 and D2 striatal projection neurons

Autor: Lucile Marion-Poll, Jean-Pierre Roussarie, Lieng Taing, Cloelia Dard-Dascot, Nicolas Servant, Yan Jaszczyszyn, Emmanuelle Jordi, Eskeatnaf Mulugeta, Denis Hervé, Déborah Bourc’his, Paul Greengard, Claude Thermes, Jean-Antoine Girault
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Communications Biology, Vol 5, Iss 1, Pp 1-16 (2022)
Druh dokumentu: article
ISSN: 2399-3642
DOI: 10.1038/s42003-022-04269-w
Popis: Striatal projection neurons expressing the D1 or D2 dopamine receptors are probed for translating mRNAs and DNA modifications, identifying differential methylation signatures between the cell types and genome-wide hydroxymethylation asymmetry between the two DNA strands.
Databáze: Directory of Open Access Journals
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