Early experiences with edoxaban for stroke prevention in atrial fibrillation in the Southeast Asia region

Autor: Alejandro Bimbo Diaz, Jeremy Chow, Fan Kee Hoo, Kok Wei Koh, Gary Chin Keong Lee, Wee Siong Teo, Narayanaswamy Venketasubramanian, Chun-Chieh Wang, Radhika Mehta
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Drugs in Context, Vol 12, Pp 1-15 (2023)
Druh dokumentu: article
ISSN: 1740-4398
DOI: 10.7573/dic.2023-3-3
Popis: Edoxaban, a once-daily, direct-acting oral anticoagulant, is approved to prevent stroke or systemic embolism in non-valvular atrial fibrillation (NVAF) and treat venous thromboembolism. The clinical benefit of edoxaban for stroke prevention in Asian patients with NVAF has been demonstrated in clinical and real-world studies. We share early clinical experiences with once-daily edoxaban and discuss its evidence-based use in patients with NVAF in Southeast Asia through several cases of patients at high risk, including frail patients, elderly patients with multiple comorbidities and patients with increased bleeding risk. These cases demonstrate the effectiveness and safety of once-daily edoxaban in patients with NVAF in Southeast Asia.
Databáze: Directory of Open Access Journals