| Autor: |
Gulizar Sokmen, Murat Sahin, Dilek Tuzun, Abdullah Sokmen, Hanife Bolat, Ayten Oguz, Adem Doganer, Huseyin Nacar, Kamile Gul |
| Jazyk: |
English<br />Portuguese |
| Rok vydání: |
2018 |
| Předmět: |
|
| Zdroj: |
Arquivos Brasileiros de Cardiologia, Vol 111, Iss 5, Pp 656-663 (2018) |
| Druh dokumentu: |
article |
| ISSN: |
1678-4170 |
| DOI: |
10.5935/abc.20180188 |
| Popis: |
Abstract Background: Majority of the incidentally discovered adrenal masses, called adrenal incidentaloma (AI), are nonfunctioning adrenal adenomas. The appropriate management of AI is still a matter debate, so it is necessary to investigate their associated morbidity. However, data regarding morphological and functional cardiac alterations are limited in this group. Objective: In this study, we aimed to assess cardiac structural and functional characteristics and atrial conduction properties in patients with nonfunctioning AI. Methods: Thirty patients with nonfunctioning AI and 46 properly matched control subjects were included in the study. After hormonal and biochemical analysis, all participants underwent transthoracic echocardiography to obtain systolic and diastolic parameters of both ventricles, in addition to atrial conduction times by tissue Doppler echocardiography. Data were analyzed with Statistical Package for the Social Sciences (SPSS, Chicago, IL, United States) statistics, version 17.0 for Windows. P < 0.05 was considered statistically significant. Results: Left ventricular (LV) mass index and LV myocardial performance index were significantly increased in AI group. Among atrial conduction times, both intra- and interatrial electromechanical delays were significantly prolonged in patients with nonfunctioning AI. Other laboratory and echocardiographic findings were similar between groups. Conclusion: Our study revealed that intra- and inter-atrial conduction times were prolonged, and LV mass index was increased in patients with nonfunctioning AI. These findings may be markers of subclinical cardiac involvement and tendency to cardiovascular complications. Close follow-up is necessary for individuals with nonfunctioning AI for their increased cardiovascular risk. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
|
