A Case of Intravascular Diffuse Large B-Cell Lymphoma Initially Suspected as Interstitial Pneumonia Associated With Systemic Scleroderma

Autor: Tomoyo Oguri MD, PhD, Shinji Sasada MD, PhD, Yuki Aramaki-Sumii MD, Yumi Tsuchiya MD, Kota Ishioka MD, Saeko Takahashi MD, PhD, Hisako Kunieda MD, Yoshifumi Kimura MD, PhD, Reishi Seki MD, Shigemichi Hirose MD, PhD, Morio Nakamura MD, PhD
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Journal of Investigative Medicine High Impact Case Reports, Vol 9 (2021)
Druh dokumentu: article
ISSN: 2324-7096
23247096
DOI: 10.1177/2324709621999226
Popis: Intravascular large B-cell lymphoma (IVLBCL) is a rare form of diffuse LBCL. The patient was a 71-year-old female admitted to our hospital with hypoxia. On admission, chest computed tomography revealed a ground-glass opacity. Interstitial pneumonia associated with systemic scleroderma was suspected because of positive anti-centromere antibody. Thereafter, steroid pulse therapy and plasma exchange were performed. Although ground-glass opacity improved, bilateral pleural effusion appeared, so we performed a random skin biopsy because of her elevated serum lactate dehydrogenase and soluble interleukin-2 receptor levels. The patient was diagnosed with IVLBCL with symptoms improving after 6 cycles of rituximab plus chemotherapy treatment.
Databáze: Directory of Open Access Journals