DIVERSE PEACH ALLERGY: SENSITIZATION TO MOLECULAR COMPONENTS OF ALLERGENS FROM PRUNUS PERSICA

Autor: M. A. Mokronosova, E. S. Korovkina
Jazyk: ruština
Rok vydání: 2014
Předmět:
Zdroj: Медицинская иммунология, Vol 15, Iss 3, Pp 215-226 (2014)
Druh dokumentu: article
ISSN: 1563-0625
2313-741X
75722739
DOI: 10.15789/1563-0625-2013-3-215-226
Popis: Abstract. Results of immunological and molecular biology investigations over last decades allowed clear to specify mechanisms of development and clinical features of allergic reactions to food of plant origin, including allergies to fruits Prunus persica - peaches and nectarines. The article contains the analysis of literature data on allergic reactions to peach, as well as clinical observations of the patients with this kind of allergy and of the results of the component component resolved diagnosis, ISAC ImmunoCAP, conducted by these patients. The collected data allow to detect two fundamentally different types of allergic reactions to Prunus persica. This is due to sensitization to allergen Pru p 3 severe systemic reaction, and due to sensitization to Pru p 1 or Pru p 4 – local response, manifesting oral allergy syndrome and associated with sensitization to pollen allergens.
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