Safety of endoscopic pancreatic necrosectomy compared with percutaneous and surgical necrosectomy: a nationwide inpatient study

Autor: Daryl Ramai, Dan M. McEntire, Kameron Tavakolian, Joseph Heaton, Saurabh Chandan, Banreet Dhindsa, Amaninder Dhaliwal, Marcello Maida, Andrea Anderloni, Antonio Facciorusso, Douglas G. Adler
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Endoscopy International Open, Vol 11, Iss 04, Pp E330-E339 (2023)
Druh dokumentu: article
ISSN: 2364-3722
2196-9736
DOI: 10.1055/a-1994-6214
Popis: Background and study aims Pancreatic necrosis is an independent predictor of morbidity and mortality among patients with acute pancreatitis. We compared the safety and outcomes of three techniques including endoscopic necrosectomy, fluoroscopy-guided percutaneous necrosectomy by an interventional radiologist, and surgical necrosectomy. Patients and methods Using the Nationwide Readmissions Database, we identified hospitalized patients who underwent pancreatic necrosectomy from 2016 to 2019. They were identified using the International Classification of Diseases, 10th Revision, Procedure Coding System. Results: Of the 2,281 patients meeting the selection criteria, the method of pancreatic necrosectomy was as follows: endoscopy (n = 672), percutaneous (n = 1,338), and surgery (n = 271). Compared to surgery, the rate of mortality was lowest for endoscopy (hazard ratio (HR) 0.27; 95 % CI 0.08–0.90; P = 0.033) followed by percutaneous (HR 0.44; 95 % CI, 0.20–0.98; P = 0.045). Endoscopy was associated with less post-procedure bleeding compared to percutaneous and surgical necrosectomy (P
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