Incidental versus symptomatic nonfunctioning pituitary adenomas: Are they different?

Autor: Vanessa Guerreiro, Fernando Mendonça, Helena Urbano Ferreira, Paula Freitas, Josué Pereira, Irene Bernardes, Jorge Pinheiro, Tiago Guimarães, Davide Carvalho
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Endocrinology, Diabetes & Metabolism, Vol 6, Iss 6, Pp n/a-n/a (2023)
Druh dokumentu: article
ISSN: 2398-9238
DOI: 10.1002/edm2.445
Popis: Abstract Background Nonfunctioning pituitary adenomas (NFPAs) constitute one of the most common tumours in the sellar region and are often discovered only when associated with compressive symptoms. With the frequent use of brain imaging, there has been an increase in the prevalence of incidentally discovered NFPAs. Aim We aim to determine the prevalence of incidental diagnosis with NPAs observed over a decade and compare the analytical, clinical and treatment differences between those who were diagnosed either incidentally or symptomatically. We also intend to evaluate the pathology differences between both groups. Methods We retrospectively analysed patients aged ≥18 years with an apparent NFPA, defined as a pituitary lesion compatible with pituitary adenoma which is not associated with the clinical or biochemical evidence of a hormone‐secreting tumour. Inclusion criteria included normal prolactin level for lesions
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