Flow Synthesis of Biologically-Relevant Compound Libraries

Autor: Pilar María Luque Navarro, Daniela Lanari
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: Molecules, Vol 25, Iss 4, p 909 (2020)
Druh dokumentu: article
ISSN: 1420-3049
DOI: 10.3390/molecules25040909
Popis: Flow chemistry is one of the most prominent enabling technologies that has greatly shaped the way chemists’ approach organic synthesis. Specifically, in drug discovery, the advantages of flow techniques over batch procedures allow the rapid and efficient assembly of compound libraries to be tested for biological properties. The aim of the present review is to comment on some representative examples from the last five years of literature that highlight how flow procedures are becoming of increasing importance for the synthesis of biologically-relevant molecules.
Databáze: Directory of Open Access Journals