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Gal Neuman,1,* Rana Swed Tobia,2,* Liron Koren,3 Ronit Leiba,4 Itai Shavit5 1Clinical Pharmacology and Toxicology Unit, 2Department of Pediatrics, Ruth Children’s Hospital, Rambam Health Care Campus, 3Rappaport Faculty of Medicine, Technion – Institute of Technology, 4Quality of Care Unit, 5Emergency Department, Ruth Children’s Hospital, Rambam Health Care Campus, Haifa, Israel *These authors contributed equally to this work Background: In the pediatric emergency department, patients are commonly treated with a single dose of oral midazolam for minor procedures. We sought to evaluate the effect of this treatment on procedure completion rates.Methods: We conducted a single-center retrospective cohort study of all patients who were treated with pre-procedure oral midazolam between January 2011 and June 2016. The primary outcome was the procedure completion rate.Results: During the study period, 1,504 patients were treated with oral midazolam as per department protocol; 1,467 received midazolam and 37 declined midazolam. Oral midazolam was used in 14 different types of emergency department procedures. The procedure completion rates in the treatment and non-treatment groups were 1,402/1,467 (95.6%) and 24/37 (64.8%), respectively (difference 30.7%; 95% confidence interval [CI] 17.3%–46.8%); p |
