Large Gastrointestinal Stromal Tumor Mimicking A Gynecologic Tumor

Autor: Sew-Khee Yeat, Heng-Ju Chen, Hun-Shan Pan, Yu-Hung Lin, Jiann-Loung Hwang, Lee-Wen Huang
Jazyk: angličtina
Rok vydání: 2005
Předmět:
Zdroj: Taiwanese Journal of Obstetrics & Gynecology, Vol 44, Iss 2, Pp 187-191 (2005)
Druh dokumentu: article
ISSN: 1028-4559
DOI: 10.1016/S1028-4559(09)60138-8
Popis: Objective: Gastrointestinal stromal tumors (GISTs) are a group of uncommon bowel tumors. We report two cases of GISTs arising from the ileum and jejunum, both of which appeared to mimic a gynecologic tumor. Case Report: In the first case, an 83-year-old, postmenopausal, woman presented with poor appetite, abdominal fullness and constipation for the preceding 3-4 days. Physical examination and imaging studies revealed a huge pelvic mass, suggestive of a huge cystic degenerated myoma. An exploratory laparotomy revealed a large tumor originating from the ileum, and immunohistochemical stains confirmed the presence of CD-117. In the second case, a 48-year-old woman presented with intermittent right lower abdominal pain and urinary frequency over the preceding 4 months. Physical examination and imaging studies revealed a pelvic mass of 21-week-gestational size. An exploratory laparotomy showed a huge fragile pelvic tumor, measuring 20 × 20 cm, arising from the jejunum. Immunohistochemical staining confirmed the presence of CD-117. Conclusion: GISTs express c-kit proteins (CD-117) on immunohistochemistry. They may mimic gynecologic tumors since they share the same pelvic cavity. One should always consider GISTs as part of the differential diagnosis in pelvic tumors.
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