Application of Taguchi method in the optimization of synthesis of cellulose-MgO bionanocomposite as antibacterial agent

Autor: Safaei Mohsen, Taran Mojtaba, Imani Mohammad Moslem, Moradpoor Hedaiat, Rezaei Farzad, Jamshidy Ladan, Rezaei Razieh
Jazyk: angličtina
Rok vydání: 2019
Předmět:
Zdroj: Polish Journal of Chemical Technology, Vol 21, Iss 4, Pp 116-122 (2019)
Druh dokumentu: article
ISSN: 1899-4741
DOI: 10.2478/pjct-2019-0047
Popis: In this study, optimal conditions to form cellulose-MgO nanocomposite with antibacterial properties were evaluated. Applying the Taguchi method, 9 experiments were designed and the effects of different concentrations of biopolymers cellulose (0.5, 1 and 2 mg/ml), MgO nanoparticles (2, 4 and 8 mg/ml) and stirring times (30, 60 and 90 min) on antibacterial activity of synthesized nanocomposites were assessed. The characterizations of products were investigated by dynamic light scattering (DLS), raman spectroscopy, scanning electron microscope (SEM), thermogravimetric analysis (TGA) and differential thermal analysis (DTA). The results showed that the nano-composite produced in the conditions of experiment 9 (MgO 8 mg/ml, cellulose 2 mg/ml and stirring time of 60 min) has the strongest antibacterial activity. The outcomes of both methods of colony forming units (CFU) and disc diffusion indicated that the antibacterial activity of cellulose-MgO nanocomposite was significantly higher than its components (P
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