A safety assessment of Coriolus versicolor biomass as a food supplement

Autor: Ana B. Barros, Jorge Ferrão, Tito Fernandes
Jazyk: angličtina
Rok vydání: 2016
Předmět:
Zdroj: Food & Nutrition Research, Vol 60, Iss 0, Pp 1-7 (2016)
Druh dokumentu: article
ISSN: 1654-661X
DOI: 10.3402/fnr.v60.29953
Popis: Background: Coriolus versicolor (CV) is a common mushroom with antitumor, anti-inflammatory, antioxidant, antiviral, antibacterial, and immunomodulatory properties. The existence of these properties has been extensively proven mainly using CV extract; research on the biomass form is scarce. Objective: The aim of this study was to investigate the safety of the CV biomass form, as it is commonly used as a food supplement. Design: CV biomass powder was dissolved in distilled water and administered daily (2.5, 5.0, and 7.5 g/kg live weight) in single doses by gavage to both female and male Charles River albino rats. Results: No adverse or lethal effects were observed as a consequence of the daily administration of CV biomass. In addition, compared with the control group, no abnormal findings were observed at necropsy and histopathological examination. Conclusions: A safe profile of CV biomass for human consumption can be inferred from the absence of any remarkable adverse effects in rats.
Databáze: Directory of Open Access Journals
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