Prevalence and genotype distribution of human papillomavirus in Czech non-vaccinated heterosexual couples

Autor: Hana Jaworek, Vladimira Koudelakova, Ivana Oborna, Blazena Zborilova, Jana Brezinova, Dagmar Ruzickova, Jana Vrbkova, Pavla Kourilova, Marian Hajduch
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Virology Journal, Vol 18, Iss 1, Pp 1-7 (2021)
Druh dokumentu: article
ISSN: 1743-422X
DOI: 10.1186/s12985-021-01551-x
Popis: Abstract Background Data about the genotype-specific human papillomavirus (HPV) prevalence in the Czech Republic is limited. We aimed to evaluate the prevalence and concordance of genotype-specific HPV infection detected in semen samples, penile swabs and cervical swabs from non-vaccinated heterosexual couples without HPV-associated disease. Methods Semen samples and penile swabs were collected from male partners and cervical swabs were collected from female partners of heterosexual couples treated for infertility (n = 195). Presence of HPV DNA in semen samples and cervical swabs was analyzed using the cobas ® HPV Test and PapilloCheck ® . Only the PapilloCheck ® test was used to detect HPV in penile swabs. The genotype-specific prevalence and concordance of HPV infection not targeted by vaccine were evaluated using Fisher exact test. Results Both partners were infected with any HPV type in 13.8% (27/195) of couples and, of these couples, 55.6% (15/27) harbored at least one mutual genotype. High-risk HPV (hrHPV) genotypes were detected in 12.3% (24/195) of semen samples, 31.3% (61/195) of penile swabs, and 19.5% (38/195) of cervical swabs (P
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