Importance of Zinc Concentration in Seminal Fluid of Men Diagnosed with Infertility

Autor: Andrea Milostić-Srb, Aleksandar Včev, Marijan Tandara, Svjetlana Marić, Vesna Kuić-Vadlja, Nika Srb, Dubravka Holik
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: Acta Clinica Croatica, Vol 59., Iss 1., Pp 154-159 (2020)
Druh dokumentu: article
ISSN: 0353-9466
1333-9451
DOI: 10.20471/acc.2020.59.01.19
Popis: The prevalence and importance of male infertility make it a serious worldwide medical and social problem. The aim of this study was to determine if there were any significant differences in zinc concentrations in seminal fluid in men diagnosed with infertility compared to control group, and if there were, to determine how it affected the number and percentage of sperm cells with normal motility and morphology. A case-control study was conducted in the Osijek-Baranja County from January 2014 to June of 2015. The study included 276 subjects referred to biochemistry laboratory of the Osijek University Hospital Centre, 100 (36.2%) of them with low sperm count confirmed by spermiogram after 3 months. Semen samples were processed according to the World Health Organization criteria, and zinc concentrations were determined using spectrophotometry and direct colorimetry without deproteinization on a chemistry analyzer (Olympus AU 680, Beckman Coulter, Tokyo, Japan). Study results showed the men with low sperm count to be significantly older (Mann Whitney U test: p=0.013) and to have lower zinc levels (χ2-test: p
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