Bridging the translational gap: adenosine as a modulator of neuropathic pain in preclinical models and humans

Autor:	Arendt-Nielsen Lars, Klitgaard Henrik, Hansen Stine N.
Jazyk:	angličtina
Rok vydání:	2023
Předmět:	adenosine neuropathic pain translation animal models human studies Special situations and conditions RC952-1245 Medicine (General) R5-920
Zdroj:	Scandinavian Journal of Pain, Vol 24, Iss 1, Pp e273-83 (2023)
Druh dokumentu:	article
ISSN:	1877-8860 1877-8879
DOI:	10.1515/sjpain-2023-0048
Popis:	This review aims to analyse the published data on preclinical and human experimental and clinical adenosine modulation for pain management. We summarise the translatability of the adenosine pathway for further drug development and aim to reveal subgroups of pain patients that could benefit from targeting the pathway.
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/fb060803b9c6427998699169292a6813 Zobrazit plný text záznamu View record in DOAJ