New perspectives of recurrent atrial fibrillation prevention in coronary heart disease patients

Autor: S. N. Tereshchenko, N. G. Chuich, P. S. Galaktionov
Jazyk: ruština
Rok vydání: 1970
Předmět:
Zdroj: Кардиоваскулярная терапия и профилактика, Vol 5, Iss 8, Pp 42-47 (1970)
Druh dokumentu: article
ISSN: 1728-8800
2619-0125
Popis: Aim. То assess clinical effectiveness of simvastatin in coronary heart disease (CHD) patients with paroxysmal atrial fibrillation (AF). Material and metliods. Thirty-two CHD patients (mean age 53+2,7 years) with paroxysmal AF and cardioversion-restored sinus rhythm were randomized into two groups. Group I (n=12) included patients receiving standard antiarrhythmic therapy and simvastatin. Group II - only standard therapy. Examination methods included: physical examination; standard 12-lead ECG with QT interval, QT dispersion (QTd), corrected QT (QTc), and QTc dispersion measurement; ECG-monitoring with assessment of heart rate (HR), incidence and features of extrasys toles, and number of ischemic ST depression episodes. laboratory tests included lipid profile and hepatic transaminase levels assessment. Results. During the follow-up period, recurrent AF incidence was significantly lower (p
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