Protein Export via the Type III Secretion System of the Bacterial Flagellum

Autor:	Manuel Halte, Marc Erhardt
Jazyk:	angličtina
Rok vydání:	2021
Předmět:	bacterial flagellum flagellar assembly type III protein export ATPase proton motive force secretion model Microbiology QR1-502
Zdroj:	Biomolecules, Vol 11, Iss 2, p 186 (2021)
Druh dokumentu:	article
ISSN:	2218-273X
DOI:	10.3390/biom11020186
Popis:	The bacterial flagellum and the related virulence-associated injectisome system of pathogenic bacteria utilize a type III secretion system (T3SS) to export substrate proteins across the inner membrane in a proton motive force-dependent manner. The T3SS is composed of an export gate (FliPQR/FlhA/FlhB) located in the flagellar basal body and an associated soluble ATPase complex in the cytoplasm (FliHIJ). Here, we summarise recent insights into the structure, assembly and protein secretion mechanisms of the T3SS with a focus on energy transduction and protein transport across the cytoplasmic membrane.
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/fae46916db554c53a69e1b4a93c76f2d Zobrazit plný text záznamu View record in DOAJ Plný text ve formátu PDF Plný text ve formátu HTML
Nepřihlášeným uživatelům se plný text nezobrazuje	K zobrazení výsledku je třeba se přihlásit.