Transcranial Direct Current Stimulation Combined with Botulinum Neurotoxin Type A Injections for Treatment of Upper Limb Intention Tremor in Multiple Sclerosis: A Case Report

Autor: Salvatore Facciorusso, Stefania Spina, Luigi Santoro, Nicoletta Cinone, Alessio Baricich, Chiara Ciritella, Pietro Fiore, Andrea Santamato
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Case Reports in Neurology, Vol 13, Iss 1, Pp 92-99 (2021)
Druh dokumentu: article
ISSN: 1662-680X
DOI: 10.1159/000512324
Popis: Upper limb intention tremor is a common cause of disability in multiple sclerosis (MS). Transcranial direct current stimulation (tDCS) is an emerging form of brain stimulation used to improve sensorimotor impairments in many neurological disorders. Here, we describe a combined therapeutic approach with botulinum neurotoxin type A (BoNT-A) and tDCS for the treatment of upper limb tremor in a patient with MS. We administered a cathodal tDCS 15 days after the injections of BoNT-A. Both post-injection and post-stimulation evaluation revealed a considerable improvement of the tremor. This approach positively affected the patient’s activities of daily living. Our case report shows a safe and beneficial effect of tDCS in the treatment of action tremor in MS especially as a possible adjunctive synergic treatment with BoNT-A injections.
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